What is heritability?
Heritability is a statistical concept that measures how much of the variation in a specific trait within a population is due to genetic differences.
Understanding Heritability
Heritability (represented as h²) describes how well differences in people’s genes account for differences in their traits, such as height, eye color, intelligence, or disorders like schizophrenia and autism spectrum disorder. An estimate of heritability is specific to one population in one environment and can change over time.
Interpreting the Scale
Heritability estimates range from zero to one:
- Close to zero: Indicates that almost all variability is due to environmental factors. Traits like religion or language spoken have a heritability of zero because they are not under genetic control.
- Close to one: Indicates that almost all variability comes from genetic differences. Disorders caused by variants in single genes, such as phenylketonuria (PKU), have high heritability.
- In the middle: Most complex traits and multifactorial diseases result from a combination of genetic and environmental factors.
Common Misconceptions
- Not a proportion of a trait: A heritability of 0.7 does not mean a trait is 70% caused by genes; it means 70% of the variability in that population is due to genetic differences.
- No information on specific genes: It does not identify which genes or environmental influences are involved.
- Heritable vs. Familial: A trait is "familial" if shared by family members, but this can be due to shared environment or lifestyle rather than genetics.
- Changeability: High heritability does not mean a trait is difficult to change (e.g., hair color is highly heritable but easily changed with dye).
Why Researchers Study It
Researchers use heritability to understand complex traits. By comparing traits in identical twins (who share almost all DNA) versus fraternal twins (who share about 50%), scientists can gain initial clues about the relative influence of "nature" (genetics) and "nurture" (environment).