Anti-Müllerian Hormone Test
The anti-müllerian hormone (AMH) test measures hormone levels in the blood to assess ovarian reserve in females and reproductive health in males.
Overview
An anti-müllerian hormone (AMH) test measures the amount of AMH in a blood sample. In males, AMH is produced by the testicles; in females, it is produced by the ovaries. Normal levels vary significantly based on age and sex.
In unborn babies, AMH is critical for the development of reproductive organs. In females of childbearing age, higher levels of AMH generally indicate a larger supply of eggs, known as ovarian reserve. As females age, the number of eggs decreases, causing AMH levels to drop until they reach zero at menopause.
What is it used for?
AMH tests are primarily used to assist in fertility treatment decisions and to diagnose specific reproductive conditions:
- Ovarian Reserve: It helps check how many eggs remain in the ovaries. While it indicates the size of the reserve, it cannot predict egg health or the ability to conceive.
- Fertility Treatment Planning: It helps providers predict how well a patient might respond to fertility medicines used in in vitro fertilization (IVF).
- Menopause Assessment: It can help identify if a patient is approaching premature or early menopause, though it cannot predict the exact timing of menopause.
- PCOS and Ovarian Cancer: It is used to monitor conditions that cause high AMH levels, such as polycystic ovary syndrome (PCOS) or certain ovarian cancers.
- Pediatric Health: In male infants, it is used to check for healthy testicular tissue in cases of undescended testicles or to investigate atypical genitalia.
Why do I need an AMH test?
Females may require this test if they are experiencing fertility problems, showing symptoms of PCOS (such as irregular periods, acne, or weight gain), or undergoing treatment for ovarian cancer. Male infants may need the test if their testicles have not descended into the scrotum, or if they are born with atypical genitalia.
What happens during the test?
A health care professional will collect a blood sample from a vein in your arm using a small needle. The process typically takes less than five minutes. There are no special preparations required for this test.
Understanding Results
Results are interpreted based on the reason for the test:
- Fertility: High levels generally mean more eggs are available; low levels suggest a shrinking egg supply.
- PCOS: High levels may be a sign of PCOS, though the test cannot diagnose the condition on its own.
- Menopause: Low levels may indicate the approach of menopause; an undetectable level confirms that a patient is in menopause.
- Ovarian Cancer: A decrease in AMH during treatment usually indicates the treatment is working, while an increase may suggest the cancer has returned.
- Male Infants: Normal levels indicate working testicles that are simply not in the correct location. Little to no AMH may indicate missing or non-functioning testicular tissue.