Adolescent idiopathic scoliosis
Adolescent idiopathic scoliosis is a common spinal abnormality characterized by a side-to-side curvature of the spine that develops during the adolescent growth spurt.
Overview
Adolescent idiopathic scoliosis involves a spine that develops an "S" or "C" shaped curvature and slight rotation. It typically appears during rapid growth in late childhood or adolescence. While mild cases are often stable, some curves are progressive and become more severe over time. Severe, progressive curves are more common in girls, though mild curvature is equally common in both sexes.
Symptoms
Mild scoliosis is often painless and may not be noticed until a physical exam or school screening. Common signs include:
- Asymmetry in the shoulders, hips, or waist
- One leg appearing longer than the other
- Visible tilt or curvature of the spine
Causes
The term "idiopathic" indicates that the exact cause is unknown. It is believed to result from a combination of environmental and genetic factors. Researchers suspect that multiple genes are involved, with some contributing to the development of the disorder and others influencing the severity or progression of the spinal curve. Potential factors under study include hormonal issues, abnormal bone or muscle growth, and nervous system abnormalities.
Inheritance
The inheritance pattern is unclear due to the involvement of multiple genetic and environmental factors. The condition can be sporadic (occurring without a family history) or cluster in families. Having a close relative with the condition increases a child's risk of developing adolescent idiopathic scoliosis.