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Blood Clots
Reviewed by Medicinsk Expert•Last updated: 2026-10-22•Blood Heart Circulation

Blood Clots

Understanding how blood clots form, the risks involved, and the symptoms to watch for can help in the early detection and management of potentially dangerous circulatory issues.

Overview

A blood clot is a mass of blood that forms when platelets, proteins, and cells in the blood stick together. When you get hurt, your body forms a blood clot to stop the bleeding. After the bleeding stops and healing takes place, your body usually breaks down and removes the blood clot. However, sometimes blood clots form where they shouldn't, your body makes too many or abnormal blood clots, or the clots don't break down like they should. These blood clots can be dangerous and may cause other health problems.

Types of Blood Clot Problems

Blood clots can form in, or travel to, the blood vessels in the limbs, lungs, brain, heart, and kidneys. The types of problems blood clots can cause depend on their location:

  • Deep vein thrombosis (DVT): A blood clot in a deep vein, usually in the lower leg, thigh, or pelvis. It can block a vein and cause damage to your leg.
  • Pulmonary embolism (PE): Occurs when a DVT breaks off and travels through the bloodstream to the lungs. A PE, especially if it is large, can damage your lungs and prevent your other organs from getting enough oxygen.
  • Cerebral venous sinus thrombosis (CVST): A rare blood clot in the venous sinuses in your brain. Normally, the venous sinuses drain blood from your brain. CVST blocks the blood from draining and can cause a hemorrhagic stroke.
  • Other locations: Blood clots in other parts of the body can cause problems such as an ischemic stroke, a heart attack, kidney problems, kidney failure, and pregnancy-related problems.

Causes & Risk Factors

Certain factors can raise your risk of developing blood clots:

  • Atherosclerosis
  • Atrial fibrillation
  • Being overweight or having obesity
  • Cancer and cancer treatments
  • Certain genetic disorders
  • Certain surgeries
  • COVID-19
  • Diabetes
  • Family history of blood clots
  • Pregnancy and giving birth
  • Serious injuries
  • Some medicines, including birth control pills
  • Smoking
  • Staying in one position for a long time, such as being in the hospital or taking a long car or plane ride

Symptoms

The symptoms for blood clots can be different, depending on where the blood clot is located:

  • In the abdomen: Abdominal pain, nausea, and vomiting.
  • In an arm or leg: Sudden or gradual pain, swelling, tenderness, and warmth.
  • In the lungs: Shortness of breath, pain with deep breathing, rapid breathing, and increased heart rate.
  • In the brain: Trouble speaking, vision problems, seizures, weakness on one side of the body, and sudden severe headache.
  • In the heart: Chest pain, sweating, shortness of breath, and pain in the left arm.

Diagnosis

To find out if you have one or more blood clots, your health care provider will:

  • Perform a physical exam.
  • Take your medical history, which includes asking about your symptoms.
  • Order blood tests, including a D-dimer test.
  • Order imaging tests, such as:
    • Ultrasound.
    • X-rays of the veins (venography) or blood vessels (angiography) taken after an injection of special dye. The dye shows up on the x-ray and allows the provider to see how the blood flows.
    • CT Scan.

Treatment & Management

Treatments for blood clots depend on where the blood clot is located and how severe it is. Treatments may include:

  • Blood thinners.
  • Other medicines, including thrombolytics. Thrombolytics are medicines that dissolve blood clots. They are usually used where the blood clots are severe.
  • Surgery and other procedures to remove the blood clots.

Prevention

You may be able to help prevent blood clots by:

  • Moving around as soon as possible after having been confined to your bed, such as after surgery, illness, or injury.
  • Getting up and moving around every few hours when you have to sit for long periods of time, for example if you are on a long flight or car trip.
  • Wearing compression stockings after surgery or during a long flight.
  • Engaging in regular physical activity.
  • Not smoking.
  • Staying at a healthy weight.

Some people at high risk may need to take blood thinners to prevent blood clots.

Frequently Asked Questions

Look for swelling, warmth, redness, or a painful cramp‑like sensation in the calf, thigh, or pelvis, especially if the leg feels heavier or tighter than usual.
Move your legs every hour (ankle pumps, calf raises), wear graduated compression stockings, stay well‑hydrated, and discuss prophylactic anticoagulants with your surgeon if you have additional risk factors.
Typically a complete blood count, kidney and liver function panels, and a coagulation profile (PT/INR or aPTT). Imaging such as Doppler ultrasound may be done if a clot is suspected, and a baseline ECG is often obtained.
Yes—these are classic emergency symptoms of a pulmonary embolism. Prompt medical attention can be life‑saving; do not wait to see if they improve.
Source: MedlinePlus, National Library of Medicine

MedlinePlus brings together authoritative health information from the National Library of Medicine (NLM), the National Institutes of Health (NIH), and other government agencies and health-related organizations.

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