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Giant Cell Arteritis
Reviewed by Medicinsk Expert•Last updated: 2026-10-22•Blood Heart Circulation

Giant Cell Arteritis

Giant cell arteritis is an inflammatory disorder primarily affecting arteries in the scalp, neck, and arms, which can lead to serious complications like permanent vision loss or stroke if not treated promptly.

Overview

Giant cell arteritis is a disorder that causes inflammation of your arteries, usually in the scalp, neck, and arms. It narrows the arteries, which keeps blood from flowing well. Giant cell arteritis often occurs with another disorder called polymyalgia rheumatica. Both are more common in women than in men. They almost always affect people over the age of 50.

Symptoms

Early symptoms of giant cell arteritis resemble the flu: fatigue, loss of appetite, and fever. Other symptoms include:

  • Headaches
  • Pain and tenderness over the temples
  • Double vision or visual loss, dizziness
  • Problems with coordination and balance
  • Pain in your jaw and tongue

Diagnosis

Your doctor will make the diagnosis based on your medical history, symptoms, and a physical exam. There is no specific test for giant cell arteritis, but you may have tests that measure inflammation.

Treatment & Management

Treatment is usually with corticosteroids. Early treatment is important; otherwise there is a risk of permanent vision loss or stroke. However, when properly treated, giant cell arteritis rarely comes back.

Frequently Asked Questions

Diagnosis relies on a combination of factors. Your doctor will take a detailed medical history, asking about your symptoms, especially headaches, vision changes, and jaw pain. A physical exam will include checking for tenderness or a reduced pulse in your temples. Blood tests to measure inflammation levels, such as erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), are often elevated. A temporal artery biopsy, where a small piece of the artery from your temple is examined under a microscope, is often used to confirm the diagnosis.
Giant cell arteritis is generally a chronic condition, but it can often go into remission with proper treatment. While there isn't a "cure" in the sense of completely eliminating the underlying tendency for inflammation, early and consistent treatment with corticosteroids usually brings the inflammation under control. Once the disease is inactive, your doctor will slowly taper your medication. Many people can eventually stop corticosteroids, and the disease rarely comes back if properly treated. However, long-term monitoring is often recommended.
The most urgent symptoms requiring immediate medical attention are sudden vision changes, such as double vision or any degree of vision loss, and new, severe, or unusual headaches, especially around the temples. Jaw pain that worsens with chewing, or tongue pain, can also be a sign of reduced blood flow. These symptoms indicate a risk of permanent vision loss or stroke if not treated promptly. Contact your doctor or seek emergency care right away if you experience them.
Corticosteroids, like prednisone, are highly effective but can have side effects, especially with long-term use. Common side effects include weight gain, elevated blood sugar, increased blood pressure, bone thinning (osteoporosis), mood changes, and increased risk of infection. Your doctor will monitor you closely for these effects and may prescribe additional medications, such as calcium and vitamin D supplements for bone health, or medications to protect your stomach. They will also work to gradually reduce your corticosteroid dose as soon as safely possible.
Source: MedlinePlus, National Library of Medicine

MedlinePlus brings together authoritative health information from the National Library of Medicine (NLM), the National Institutes of Health (NIH), and other government agencies and health-related organizations.

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