Pregnancy Test
Pregnancy tests detect the hormone human chorionic gonadotropin (hCG) in urine or blood to confirm pregnancy.
Overview
The placenta produces hCG after a fertilized egg attaches to the uterine wall. Levels of this hormone typically double every three days during the first ten weeks of pregnancy. hCG is essential for thickening the uterine lining, preparing the body for labor, and stopping menstrual periods.
Types of Tests
- Urine tests: Can be performed at home or in a clinic. They are 97–99% accurate when taken a week or two after a missed period.
- Blood tests: Performed in a lab. They can detect smaller amounts of hCG earlier than urine tests but are less commonly used for routine pregnancy confirmation.
Clinical Uses of Quantitative Blood Tests
Quantitative blood tests measure the exact amount of hCG and are used to:
- Determine fetal age in early pregnancy.
- Monitor high-risk pregnancies for potential miscarriage.
- Check for ectopic pregnancy or molar pregnancy.
- Screen for birth defects or chromosome problems (e.g., Down syndrome).
- Monitor certain cancers (e.g., ovarian or testicular).
Symptoms of Early Pregnancy
Common signs include:
- Missed period
- Swollen, tender breasts
- Fatigue
- Frequent urination
- Nausea and vomiting (morning sickness)
- Bloating
Important Considerations
- False-negatives: Occur if a test is taken too early when hCG levels are not yet high enough to detect. If a test is negative but you suspect pregnancy, repeat the test in one week.
- False-positives: Can occur if you are taking fertility medications.
- Preparation: For urine tests, avoid drinking large amounts of fluid beforehand to prevent diluting the sample. Using the first morning urine is recommended for the highest accuracy.